NICHD BRAIN AND TISSUE BANK

Publications Utilizing Tissue Donations

AREA OF RESEARCH

Tay-Sachs Disease

Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation. Wada, R., Tifft, C. and Proia, R. PNAS, 97: 10954-10959, 2000. [paper]

Presence of an Unusual GM2 Derivative, Taurine-conjugated GM2, in Tay-Sachs Brain. Li, Y., Maskos, K., Chou, C., Cole, R. and Li, S. The Journal of Biological Chemistry 278: 35286-35291, 2003. [paper]